Data in Europe and China showing weaker demand under inflationary pressure caused equities to end a 3-day session of gains, with concerns of a global recession putting investors in a cautious mood.
The ISM survey's key purchasing management index (PMI) data saw manufacturing activity in the United States (US) decline in July, but still in expansion territory and long-term supply constraints appear to be easing.
In addition, the European and Asian regions also exhibited slow and contracted manufacturing activity behind a weak demand situation and continued inflationary pressures.
The streak, the major indices on Wall Street ended the trading session on a low note with many giving back some gains.
The Dow Jones Industrial Average fell 0.14% to 32,798.4, the S&P 500 lost 0.28% to 4,118.61 and the Nasdaq Composite was down 0.18% to 12,368.98.
The pan-European STOXX 600 index lost 0.19% and MSCI's gauge of worldwide shares rose 0.06%.
Meanwhile, emerging market shares lost 0.06% while MSCI's broadest Asia-Pacific index outside Japan closed 0.11% while the Nikkei added 0.69%.
Commenting on the current market situation, Chuck Carlson of Horizon Investment Services stated that investors are following developments and watching for any signs of a downward trend.
Currency trends saw the dollar index drop 0.47% with the Euro up slightly by 0.38% at $1.0257 while the Japanese Yen remained up 1.20% at $131.64.
The benchmark 10-year note rose 15/32 in price to yield 2.5893% from 2.642% while the 30-year bond rose 35/32 in price to yield 2.9206% at 2.977%.
For commodities, US crude fell 4.73% at $93.89 and Brent crude fell 3.94% at $100.03.
Spot gold was traded up 0.4% at $1,771.89.
