US stocks closed lower after posting gains last week on expectations of a rate cut by the Federal Reserve (Fed).
Investors are now focused on key economic data, with several Fed officials including Chairman Jerome Powell scheduled to speak this week.
Powell is expected to deliver his speech on Wednesday at 12:35 am Malaysia time.
He is likely to highlight inflation and labor market developments in his speech, while stressing that the direction of interest rates remains data-dependent.
The S&P 500 index fell 0.1% to 6,715.25 points, the Dow Jones fell 0.1% to 46,587.0 points, while the technology-focused Nasdaq fell 0.1% to 24,849.50 points.
Investors were also watching for any new clues from the Fed on interest rates after the central bank emphasized a data-dependent approach to any further easing measures.
In other news, September's Purchasing Managers' Index (PMI) data will be released on Monday at 8:45pm Malaysia time, which is expected to provide further insight into US business activity.
Meanwhile, the Personal Consumer Expenditures (PCE) Price Index, the Fed's preferred inflation gauge, will be released on Friday, providing a clearer signal on the central bank's plans to cut interest rates.
Core PCE inflation is expected to remain above the Fed's 2% annual target, with particular attention being paid to the possibility of additional price pressures from rising trade tariffs.
